Chicken Alfredo Lasagna

Featured in: Pecan-Warm Cozy Dinners

This rich and comforting dish features succulent shredded chicken combined with a velvety Alfredo sauce, layered with spinach, ricotta, and mozzarella between tender pasta sheets.

Baked until golden and bubbly, it delivers authentic Italian-American flavors with a modern twist. Perfect for family dinners or entertaining guests.

Ready in 1 hour 25 minutes with medium difficulty level. Serves 8 and pairs beautifully with a crisp salad and wine.

Updated on Sun, 18 Jan 2026 13:55:00 GMT
Freshly baked Chicken Alfredo Lasagna with melted mozzarella and golden, bubbly cheese topping served hot. Save to Pinterest
Freshly baked Chicken Alfredo Lasagna with melted mozzarella and golden, bubbly cheese topping served hot. | pecanfield.com

The steam fogging up my kitchen window, the smell of garlic and cream mingling in the air, my daughter asking if we could have this every Sunday. That was the night I realized this lasagna wasn't just dinner, it was the kind of dish that turns a regular weeknight into something people remember. I'd been tinkering with the idea of swapping red sauce for Alfredo, and when I pulled that bubbling, golden pan from the oven, even I was surprised by how right it looked. The layers held together beautifully, the chicken stayed tender, and the spinach added just enough color to make it feel less heavy. It became our go-to for birthdays, potlucks, and those evenings when only comfort food will do.

I made this for my brother's family the first time, and his kids, who normally pick apart anything green, devoured it without a single complaint. My sister-in-law asked for the recipe twice before they even left. That's when I knew it had staying power. It's become the dish I bring when someone needs a meal, when I want to feel like I've really fed people, not just filled them up.

Ingredients

  • Cooked chicken breast: I usually grab a rotisserie chicken and shred it, saves time and adds a little extra flavor from the seasoning.
  • Lasagna noodles: Oven-ready noodles work great if you're in a hurry, but I prefer boiling regular ones for better texture and control.
  • Baby spinach: It wilts down to almost nothing, so don't be shy, it adds color and a bit of earthiness without overpowering the cream.
  • Onion and garlic: These build the base flavor, sauteing them until soft makes all the difference in avoiding any sharpness.
  • Alfredo sauce: Store-bought is fine, but if you have 10 extra minutes, homemade is silkier and you can control the salt.
  • Ricotta cheese: Whole milk ricotta gives you the creaminess you want, low-fat versions can turn grainy.
  • Mozzarella and Parmesan: Mozzarella melts into those gooey layers, Parmesan adds the nutty, salty finish on top.
  • Egg: It binds the ricotta mixture so it doesn't slide apart when you slice into it.
  • Italian herbs: A simple blend of basil, oregano, and thyme ties everything to that Italian comfort we're after.
  • Fresh parsley: Optional, but a sprinkle at the end makes it look like you fussed more than you did.

Instructions

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Get the oven ready:
Preheat to 375 degrees and grease your 9x13 inch baking dish lightly with butter or oil. This keeps the bottom layer from sticking and makes cleanup easier.
Prep the noodles:
If you're using regular lasagna noodles, boil them until just al dente, then drain and lay them flat so they don't stick together. Oven-ready noodles skip this step entirely.
Cook the aromatics:
In a skillet over medium heat, saute the diced onion in a little olive oil until it's soft and translucent, about 3 to 4 minutes. Add the minced garlic and stir for another minute until fragrant.
Wilt the spinach:
Toss in the chopped spinach and cook just until it wilts down, about 2 minutes. Remove from heat and let it cool so it doesn't scramble the egg later.
Mix the ricotta filling:
In a medium bowl, combine ricotta, egg, half the Parmesan, Italian herbs, salt, and pepper, then fold in the cooled spinach mixture. It should be thick and creamy.
Start layering:
Spread half a cup of Alfredo sauce on the bottom of your baking dish to prevent sticking. Lay down 4 noodles, then spread half the ricotta spinach mixture over them.
Add chicken and sauce:
Scatter half the shredded chicken over the ricotta layer, drizzle with 1 cup of Alfredo sauce, and sprinkle with about two thirds of a cup of mozzarella. Press gently so everything settles.
Repeat the layers:
Add another layer of 4 noodles, the remaining ricotta spinach mixture, the rest of the chicken, another cup of Alfredo, and another two thirds cup of mozzarella. You're building a sturdy, saucy tower.
Top it off:
Finish with the last 4 noodles, pour the remaining Alfredo sauce over the top, and cover with the rest of the mozzarella and Parmesan. The cheese should blanket the whole surface.
Bake covered:
Cover the dish tightly with foil and bake for 30 minutes. The foil traps steam and helps everything cook through without drying out.
Finish uncovered:
Remove the foil and bake for another 20 to 25 minutes until the top is bubbly and golden brown. The edges should be sizzling.
Rest before serving:
Let the lasagna stand for 10 to 15 minutes before slicing. This lets the layers set so your slices hold together instead of sliding into a puddle.
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Layers of tender chicken, creamy Alfredo sauce, spinach, and pasta in a slice of Chicken Alfredo Lasagna. Save to Pinterest
Layers of tender chicken, creamy Alfredo sauce, spinach, and pasta in a slice of Chicken Alfredo Lasagna. | pecanfield.com

One evening, I served this to a friend who swore she didn't like chicken in pasta dishes. She had two servings and texted me the next day asking if I'd bring it to her birthday dinner. That's when I stopped worrying about whether people would find it too rich or too different. Sometimes you just trust the combination of butter, cream, and good intentions, and it all works out.

Making It Your Own

This lasagna is forgiving, which means you can swap things around based on what's in your fridge. I've used kale instead of spinach when that's what I had, and it added a bit more bite. You can toss in sauteed mushrooms for earthiness or even a handful of sun-dried tomatoes if you want a little tang. If you're feeling fancy, a pinch of nutmeg in the ricotta mixture adds a subtle warmth that makes people ask what the secret is. Just don't overdo it, a tiny pinch is all you need.

Storing and Reheating

Leftovers keep in the fridge for up to four days, and honestly, they taste even better after a night of sitting. I reheat individual portions in the microwave covered with a damp paper towel to keep them from drying out. If you're reheating a bigger piece, cover it with foil and warm it in a 325 degree oven for about 20 minutes. You can also freeze this, either the whole pan or individual slices wrapped tightly in foil and plastic. Just thaw overnight in the fridge before reheating.

Serving Suggestions

This lasagna is rich enough to be the star, so I keep sides simple. A crisp green salad with lemon vinaigrette cuts through the creaminess beautifully. Garlic bread is always a hit, though it's not exactly necessary since there's plenty of carbs already. I like serving it with a glass of Pinot Grigio or a light Chardonnay, something that won't compete with all that Alfredo.

  • Pair with a Caesar salad for a classic Italian-American feel.
  • Add roasted broccoli or green beans if you want more vegetables on the plate.
  • Serve with a crusty baguette for soaking up any extra sauce.
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Rustic white dish of Chicken Alfredo Lasagna garnished with parsley, ready to serve with a side salad. Save to Pinterest
Rustic white dish of Chicken Alfredo Lasagna garnished with parsley, ready to serve with a side salad. | pecanfield.com

This is the kind of recipe that feels like a hug on a plate, the kind you make when you want people to leave your table feeling taken care of. I hope it becomes one of those dishes you turn to again and again.

Questions & Answers

Can I prepare this ahead of time?

Yes, assemble the entire dish, cover with foil, and refrigerate for up to 24 hours before baking. Add 10-15 minutes to the baking time if baking from cold.

What's the best way to achieve the perfect texture?

Cook lasagna noodles to al dente, then bake covered for 30 minutes to trap steam, creating tender layers. Uncover for the final 20-25 minutes to achieve a golden, crispy top.

How do I prevent a watery lasagna?

Ensure spinach is well-drained after wilting and squeeze out excess moisture. Use quality ricotta cheese and don't overmix the filling.

Can I substitute the Alfredo sauce?

Homemade Alfredo works wonderfully and takes about 10 minutes. For variations, try a light cream sauce with garlic or a pesto-cream hybrid.

What wine pairs best with this dish?

Pinot Grigio complements the creamy Alfredo beautifully with its crisp acidity. Alternatively, try Sauvignon Blanc or a light Chardonnay.

How should I store leftovers?

Refrigerate in an airtight container for up to 3 days. Reheat individual portions in the microwave or cover and warm in a 350°F oven for 15-20 minutes.

Chicken Alfredo Lasagna

Tender chicken, creamy Alfredo sauce, fresh spinach, and melted mozzarella layered between pasta for an Italian-American comfort classic.

Prep Time
30 minutes
Time to Cook
55 minutes
Total Duration
85 minutes
Created by Michael Allen


Skill Level Medium

Cuisine Italian-American

Makes 8 Portions

Diet Preferences None specified

What You'll Need

Proteins

01 3 cups cooked chicken breast, shredded or diced

Pasta

01 12 lasagna noodles, regular or oven-ready

Vegetables

01 2 cups fresh baby spinach, roughly chopped
02 1 medium onion, finely diced
03 3 cloves garlic, minced

Sauces & Dairy

01 4 cups Alfredo sauce, store-bought or homemade
02 2 cups whole milk ricotta cheese
03 2 cups shredded mozzarella cheese
04 1 cup grated Parmesan cheese
05 1 large egg

Spices & Seasonings

01 1 teaspoon dried Italian herbs
02 1/2 teaspoon salt
03 1/4 teaspoon black pepper
04 2 tablespoons olive oil

Garnish

01 2 tablespoons fresh parsley, chopped

How to Make It

Step 01

Prepare Baking Dish: Preheat oven to 375°F. Lightly grease a 9x13-inch baking dish with oil or cooking spray.

Step 02

Cook Pasta: Cook lasagna noodles according to package instructions until al dente. Drain thoroughly and set aside on a clean surface.

Step 03

Sauté Aromatics: Heat olive oil in a skillet over medium heat. Sauté diced onion for 3-4 minutes until softened. Add minced garlic and cook for 1 minute.

Step 04

Wilt Spinach: Stir in chopped spinach and cook until completely wilted, approximately 2 minutes. Remove from heat and cool slightly.

Step 05

Prepare Ricotta Mixture: In a medium bowl, combine ricotta cheese, egg, half the Parmesan cheese, Italian herbs, salt, and pepper. Fold in cooled spinach mixture until evenly distributed.

Step 06

Layer First Base: Spread 1/2 cup Alfredo sauce on the bottom of prepared baking dish.

Step 07

Assemble First Layer: Place 4 noodles over sauce. Spread half the ricotta-spinach mixture over noodles. Distribute half the shredded chicken evenly. Drizzle with 1 cup Alfredo sauce and sprinkle with 2/3 cup mozzarella cheese.

Step 08

Assemble Second Layer: Repeat layering with 4 noodles, remaining ricotta-spinach mixture, remaining chicken, 1 cup Alfredo sauce, and 2/3 cup mozzarella cheese.

Step 09

Add Final Layer: Top with final 4 noodles, remaining Alfredo sauce, remaining mozzarella cheese, and remaining Parmesan cheese.

Step 10

Bake Covered: Cover baking dish tightly with aluminum foil. Bake at 375°F for 30 minutes.

Step 11

Bake Uncovered: Remove foil and continue baking for 20-25 minutes until top is bubbly and golden brown.

Step 12

Rest Before Serving: Remove from oven and let stand for 10-15 minutes. This allows the lasagna to set and makes slicing cleaner. Garnish with fresh parsley before serving.

Tools Needed

  • 9x13-inch baking dish
  • Large skillet
  • Medium mixing bowl
  • Saucepan for Alfredo sauce preparation
  • Measuring cups and spoons
  • Aluminum foil

Allergy Details

Always check your ingredients for allergens and talk to your healthcare provider if you're unsure.
  • Contains wheat from pasta
  • Contains milk and dairy products
  • Contains eggs
  • May contain tree nuts if using nut-based Alfredo sauce
  • Always verify ingredient labels for potential hidden allergens

Nutrition Facts (per portion)

Provided for general knowledge—ask your doctor for personalized advice.
  • Energy: 510
  • Fats: 27 g
  • Carbohydrates: 33 g
  • Proteins: 34 g