Roasted Garlic Chicken Penne

Featured in: Pecan-Warm Cozy Dinners

Roasted Garlic Chicken Penne combines perfectly cooked penne pasta with tender roasted chicken breasts, all enveloped in a luxurious roasted garlic cream sauce. The dish features a homemade sauce made from roasted garlic cloves, creamy milk, heavy cream, and Parmesan cheese, creating rich and aromatic flavors. This Italian-American main course takes just 50 minutes from start to table, making it ideal for weeknight dinners or entertaining guests. The preparation involves roasting garlic and chicken simultaneously in the oven before building a silky sauce on the stovetop. Finishing with fresh parsley and extra Parmesan elevates the presentation and taste.

Updated on Tue, 20 Jan 2026 14:56:00 GMT
Fresh roasted garlic chicken penne pasta in a creamy sauce topped with chopped parsley and Parmesan. Save to Pinterest
Fresh roasted garlic chicken penne pasta in a creamy sauce topped with chopped parsley and Parmesan. | pecanfield.com

The first time I made this pasta, my apartment smelled like an Italian restaurant for days. My roommate kept wandering into the kitchen, asking what I was cooking that smelled so incredible. Now whenever I roast garlic, I always do extra heads just to spread on bread as a snack while the rest of the dish comes together.

I served this at a small dinner party last winter when my friend was going through a tough breakup. She took three bowls and finally looked up and said this is exactly what I needed. Food has this way of being more than nourishment sometimes.

Ingredients

  • 2 large boneless skinless chicken breasts: I pound them slightly to even thickness so they cook evenly and stay juicy
  • 340 g (12 oz) penne pasta: The ridges catch all that roasted garlic cream sauce beautifully
  • 1 large head garlic: Roasting mellows the sharp bite into something sweet and almost caramel-like
  • 1 tsp olive oil: Just enough to help the garlic roast without drying out
  • 2 tbsp unsalted butter: Forms the base of our roux for that silky texture
  • 2 tbsp all-purpose flour: Thickens the sauce into something luscious and coating
  • 400 ml (1 2/3 cups) whole milk: The creaminess foundation, do not swap for skim here
  • 120 ml (1/2 cup) heavy cream: Adds that luxurious restaurant-quality finish
  • 60 g (2 oz) grated Parmesan cheese: Freshly grated melts better than pre-shredded
  • 1/2 tsp salt: Adjust based on your personal preference and saltiness of Parmesan
  • 1/4 tsp freshly ground black pepper: Freshly ground makes a noticeable difference
  • 1/4 tsp crushed red pepper flakes: Optional but I love the subtle warmth it adds
  • 2 tbsp chopped fresh parsley: Brings a bright pop of color and fresh flavor against the rich sauce

Instructions

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Roast the garlic:
Cut the top off your garlic head, drizzle with olive oil, wrap in foil, and roast at 200°C (400°F) for 30 minutes until cloves are soft and golden.
Cook the chicken:
Season chicken breasts with salt and pepper, place on a baking sheet, and roast alongside the garlic for 22 to 25 minutes until internal temperature reaches 74°C (165°F).
Boil the pasta:
Cook penne in salted boiling water until al dente, then drain while reserving 120 ml (1/2 cup) of the starchy pasta water.
Prep the roasted garlic:
Squeeze the soft cloves from their skins and mash them into a smooth paste.
Make the sauce base:
Melt butter over medium heat, whisk in flour for 1 minute, then gradually whisk in milk and cream until thickened.
Add the flavor:
Stir in mashed garlic, Parmesan, salt, pepper, and red pepper flakes until cheese melts and sauce is smooth.
Bring it together:
Add sliced chicken and cooked penne to the sauce, tossing to coat and adding pasta water as needed.
Serve:
Plate immediately garnished with fresh parsley and extra Parmesan.
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A close-up of tender penne tossed with sliced roasted chicken in a velvety garlic cream sauce. Save to Pinterest
A close-up of tender penne tossed with sliced roasted chicken in a velvety garlic cream sauce. | pecanfield.com

Last week my daughter helped me make this and announced she wants to learn to cook real meals, not just help stir. We made extra sauce and she dipped bread in it while standing at the counter, just like I used to do at my grandmother house.

Making It Ahead

You can roast the garlic and cook the chicken up to two days in advance. Store them separately in the refrigerator and reheat gently while making the sauce. The pasta should always be cooked fresh though, leftover pasta never quite comes back to life the same way.

Adding Vegetables

Sautéed mushrooms or spinach work beautifully in this sauce. Add them after the sauce has thickened but before adding the pasta, letting them simmer for just a couple minutes. The mushrooms soak up all that garlicky goodness and become incredibly flavorful.

Wine Pairing

A crisp Pinot Grigio cuts through the richness while complementing the roasted garlic. Light Chardonnay works too if you prefer something with a bit more body. Pour a glass for yourself while cooking, the sauce gets even better when the chef is relaxed.

  • Chill your wine glass while the oven heats up
  • Use leftover wine to deglaze the pan if making add-ons
  • Serve the same wine you cooked with for a thoughtful touch
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Golden roasted garlic cream sauce coating chicken penne pasta served with a glass of Pinot Grigio. Save to Pinterest
Golden roasted garlic cream sauce coating chicken penne pasta served with a glass of Pinot Grigio. | pecanfield.com

This is the kind of recipe that turns a random Tuesday into something worth remembering. Hope it becomes a regular in your rotation too.

Questions & Answers

How do I know when the roasted chicken is done?

The chicken is ready when it reaches an internal temperature of 74°C (165°F) on a meat thermometer. You can also check by piercing the thickest part—the juices should run clear with no pink coloring.

Can I make this dish ahead of time?

You can prepare the components separately: roast the garlic and chicken up to 2 days ahead, and make the sauce up to 1 day in advance. Combine everything just before serving and gently reheat over medium-low heat, adding pasta water if needed to restore creaminess.

What can I substitute for heavy cream?

You can replace heavy cream with an equal amount of Greek yogurt, sour cream, or half-and-half. For a lighter version, use additional whole milk, though the sauce will be less rich. Stir any substitute in gently at the end to prevent curdling.

Why is my sauce too thick or too thin?

If too thick, gradually whisk in reserved pasta water to achieve your desired consistency. If too thin, simmer uncovered for 2-3 minutes to reduce and thicken naturally. The starchy pasta water helps emulsify and bind the sauce beautifully.

How should I store leftovers?

Store in an airtight container in the refrigerator for up to 3 days. Reheat gently over medium-low heat in a skillet, adding a splash of milk or pasta water to restore the sauce's silky texture. Avoid high heat, which can cause the cream to separate.

What wine pairs well with this dish?

A crisp Pinot Grigio or light Chardonnay complements the roasted garlic and creamy sauce beautifully. The wine's acidity cuts through the richness of the cream while enhancing the delicate garlic flavors.

Roasted Garlic Chicken Penne

Tender penne tossed with roasted chicken in a silky, aromatic garlic cream sauce—deeply satisfying and ready in under an hour.

Prep Time
15 minutes
Time to Cook
35 minutes
Total Duration
50 minutes
Created by Michael Allen


Skill Level Medium

Cuisine Italian-American

Makes 4 Portions

Diet Preferences None specified

What You'll Need

Proteins

01 2 large boneless, skinless chicken breasts (14 oz)

Pasta

01 12 oz penne pasta

Roasted Garlic

01 1 large head garlic
02 1 teaspoon olive oil

Cream Sauce

01 2 tablespoons unsalted butter
02 2 tablespoons all-purpose flour
03 1⅔ cups whole milk
04 ½ cup heavy cream
05 2 oz grated Parmesan cheese
06 ½ teaspoon salt
07 ¼ teaspoon freshly ground black pepper
08 ¼ teaspoon crushed red pepper flakes (optional)

Garnish

01 2 tablespoons chopped fresh parsley
02 Extra grated Parmesan cheese, to serve

How to Make It

Step 01

Preheat oven: Set oven temperature to 400°F.

Step 02

Prepare garlic for roasting: Slice the top off the garlic head to expose cloves. Drizzle with 1 teaspoon olive oil and wrap tightly in foil.

Step 03

Roast garlic: Place wrapped garlic in oven and roast for 30 minutes until soft and golden brown.

Step 04

Prepare and roast chicken: Season chicken breasts with salt and pepper. Place on baking sheet and roast alongside garlic for 22 to 25 minutes until internal temperature reaches 165°F. Allow to rest before slicing thinly.

Step 05

Cook pasta: Bring salted water to boil in large pot. Add penne and cook according to package directions until al dente. Drain and reserve ½ cup pasta water.

Step 06

Extract roasted garlic: Squeeze softened garlic cloves from their skins into a small bowl and mash to smooth paste.

Step 07

Create roux base: Melt butter in large skillet over medium heat. Whisk in flour and cook for 1 minute, stirring constantly.

Step 08

Build cream sauce: Gradually whisk milk and cream into flour mixture, stirring constantly for 3 to 4 minutes until sauce thickens.

Step 09

Season sauce: Stir in mashed roasted garlic, Parmesan cheese, salt, pepper, and red pepper flakes if desired. Cook until cheese melts and sauce becomes smooth.

Step 10

Combine components: Add sliced chicken and cooked penne to sauce. Toss to coat evenly, adding reserved pasta water gradually to achieve desired consistency.

Step 11

Finish and serve: Transfer to serving plates. Garnish with fresh parsley and additional Parmesan cheese. Serve immediately.

Tools Needed

  • Chef's knife
  • Baking sheet
  • Aluminum foil
  • Large pot
  • Colander
  • Large skillet
  • Whisk

Allergy Details

Always check your ingredients for allergens and talk to your healthcare provider if you're unsure.
  • Contains wheat gluten
  • Contains milk and dairy products
  • May contain eggs depending on pasta brand

Nutrition Facts (per portion)

Provided for general knowledge—ask your doctor for personalized advice.
  • Energy: 670
  • Fats: 24 g
  • Carbohydrates: 72 g
  • Proteins: 41 g